Takuma Suematsu
Research Assistant Professor
RNA processing mechanism in trypanosomal mitochondria
My research focuses on elucidating the molecular basis of RNA processing within unique organellar gene expression systems. I aim to uncover how RNA maturation and processing are orchestrated through the coordinated actions of RNA-binding proteins and enzymes, and how these mechanisms differ from those in humans. Using the mitochondrial gene expression system of the parasitic protozoan Trypanosoma brucei as a model, I investigate the structure, function, and interactions of protein complexes involved in mitochondrial RNA processing and translation. Through this mechanistic understanding, my goal is to reveal fundamental principles of organellar gene expression and to provide molecular insights that may guide the development of novel anti-parasitic strategies.
